As we learned in the finale, Jane is being poisoned by ZIP, the very drug used to wipe her memory at the premiere of the series. Also suffering from the disease, her brother was searching for a cure and hid caches of data all over the globe. The team will follow a trail of cryptic breadcrumbs that lead to all-new crimes to solve and, with any luck, a cure to save Jane. Weller is on the brink of death, Remi returned from the depths of Jane's mind and Zapata working with the bad guys. Not knowing that Zapata has joined the villainous HCI Global, Reade tries desperately to find her. At the same time, Patterson hunts to cure Jane with Rich DotCom.
